SCN1A mutations are the main cause of the epilepsy disorders Dravet syndrome (DS) and genetic epilepsy with febrile seizures plus (GEFS+). Mutations that reduce the activity of the mouse Scn8a gene. in contrast. are found to confer seizure resistance and extend the lifespan of mouse models of DS and GEFS+. https://www.macorners.shop/product-category/pickleball-paddle-cover/